Antimicrobial peptides in gastrointestinal diseases

Antimicrobial peptides (AMPs) are host defence peptides that carry out multiple roles in the gastrointestinal (GI) tract.

This title presents knowledge about the physiological functions and pharmacological actions of AMPs in inflammation, cancer, and further infection of the GI tract.

The book provides coverage from the basic research to clinical application for GI diseases.

Current research and development of AMPs is presented, opening the way for further work on these peptides, not only in the context of GI diseases, but also for similar pathologies in other organs.

AMPs are key to the regulation of human microbiome and second line defence in the GI mucosa, prevent colonization of pathogens and modulation of innate response to invading pathogens, and modify immunological reactions during inflammatory processes and oncogenic development in the GI mucosa.