Helicobacter pylori : basic mechanisms to clinical cure, 2002

H. pylori infection, both in man and in the laboratory animal, has become a standard model to investigate fundamental problems in biology, such as microbial-host interactions, intracellular signalling, modulation of inflammation, mucosal atrophic metaplasia, and microbial resistance, to name just a few.

The issues addressed in this book are grouped according to their leading theme.

Topics include: the new Helicobacters, strain differences of H. pylori and their consequence on microbial-host interactions and the effects of H. pylori infection on the gastric mucosa. The role of H. pylori is explained in relation to: gastric carcinogenesis; gastroesophageal reflux disease; dyspepsia and long-term acid suppression.

Eradication therapies are reviewed with respect to their global consequences and problems.

The last two sections are devoted to a global update on therapeutic indications and finally on priorities for further research.

These proceedings accurately reflect the state-of-the-art presentations delivered by world experts.

This latest volume will further enrich this top-class series on H. pylori infection.