Medicinal Chemistry for the 21st Century

The new Chemistry for the 21st Century series is a collection of specialist monographs which consist of review papers written by scientists of world renown from a variety of countries.

Each volume outlines the perspectives of various fields of chemistry in opening up new horizons for science and technology.

This new addition to the Series contains contributions from leading scientists selected from the fields of medicinal chemistry and pharmacology and will serve as a guide for professionals to the future direction of medicinal chemical development.

Medicinal Chemistry for the 21st Century is divided into four major sections as follows: Part I: New Lead Discovery : Historical perspectives; Strategies for the creation of new drugs Part II: Protein Structure-function relationships : Cloning and structural studies on receptors and enzymes; Detection of new enzymes and receptors by hybridization technique; Signal transduction mechanisms.

Part III: Pharmacophore studies : Pharmacophore mimickry modelling; Synthesis of peptido-mimetics; Optimization Part IV: Bioavailability manipulation : Prodrugs; Drug targeting.