TRP Channels in Health & Disease : Implications for Diagnosis & Therapy

Changes in temperature, either hot or cold, is sensed through direct activation of members of the temperature-sensitive transient release potential (TRP) ion channel superfamily, the so-called "thermoTRPs".

Of the 28 TRP channels discovered today, seven sense hot or warm temperatures whereas two are activated by cold.

Together, these channels cover a wide temperature range with extremes that fall between 10 C and 53 C.

This new and unique book reviews research on TRP channels and their relation to health and disease.