Alzheimer Disease, Down Syndrome and Their Relationship

This study considers in depth the remarkable association between Down Syndrome and Alzheimer disease.

It provides overviews of each disorder, followed by detailed accounts and analyses of hypotheses that attempt to account for the presence of Down Syndrome as a risk factor for Alzheimer disease.

The data and discussions presented, including practical diagnostic and management recommendations, should interest health professionals involved in caring for adults with Down Syndrome and researchers exploring biological and behavioural aspects of the intriguing link between the two disorders.