The Molecular Basis of Skeletogenesis

Skeletogenesis is the study of normal and abnormal skeletal development, and the processes regulating the development of the human skeleton, such as human genetic syndromes and bone remodelling.

This text offers an insight into the mechanisms of normal and abnormal skeletogenesis via a cross-fertilization of ideas covering human molecular genetics, developmental biology, tissue biology and the biochemistry of cell signal pathways.

It provides a broad perspective, which is essential in understanding the aetiology of genetic diseases affecting skeletal development.