Chronic Lymphocytic Leukaemia : Scientific Advances and Clinical Developments

Presents the current knowledge of the biology and immunology of chronic lymphocytic leukemia (CLL) and how it relates to the pathogenesis, diagnosis and oratory and therapy of this common form of leukemia - focusing on laboratory and clinical research and the state-of-the-art approach to patients with CLL.

The book describes the pathogenesis of immunodeficiency and disordered immunity in CLL, evaluates the immunologic and therapeutic implications of cross-reactive idiotypes in CLL and provides evidence for clonal evolution and its clinical relevance.

Referenced with nearly 1650 bibliographic citations, this book should prove a valuable resource for oncologists, hematologists, immunologists, pathologists, infectious disease specialists, internists and molecular biologists.