Mechanisms of Immune Regulation

The dramatic increase in our knowledge of immune processes, which has taken place over recent years, has led to new approaches to the understanding and treatment of disease.

The purpose of this book is to present the physiological mechanisms of immune regulation in the light of the new information, and to indicate the effect of this knowledge on selected clinical questions.

Among the topics reviewed are T and B cell tolerance, clonal deletion, suppressor cells, mechanisms of immune privileged sites and experimental models of tumour immunity. Oral tolerance, ultraviolet radiation and photosensitized effects on immunity, allograft management, T cell vaccination and regulation of immunity with T cell epitopes are discussed from the point of view of possible therapeutic application.

Immunologists, molecular and cell biologists, oncologists, pharmacologists and those working in the pharmaceutical field will find this work of particular interest.