HIV-associate cardiovascular disease : clinical and biological insights

International specialists examine therapeutic choices for the treatment of myocardial cell dysfunction in HIV disease, with a focus on knowledge in both clinical and biological aspects of HIV-associated cardiovascular disease.

Topics covered include research findings from experimental work on transgenic mice; the role of cytokines in the development of HIV-associated cardiomyopathy and pulmonary hypertension (with related diagnostic and therapeutic implications); and the relationship between dilated cardiomyopathy and encephalopathy in HIV-infected adults and children.

The detrimental cardiovascular effects of drugs such as reverse transcriptase inhibitors and protease inhibitors, which have significantly changed the natural history of HIV disease, are also discussed.