Microarrays for an integrative genomics

Functional genomics - the deconstruction of the genome to determine the biological function of genes and gene interactions - is one of the most fruitful new areas of biology.

The growing use of DNA microarrays allows researchers to assess the expression of tens of thousands of genes at a time.

This quantitative change has led to qualitative progress in our ability to understand regulatory processes at the cellular level.

This book provides a systematic introduction to the use of DNA microarrays as an investigative tool.

The presentation is appropriate for readers from biology or bioinformatics.

After presenting a framework for the design of microarray-driven functional genomics experiments, the book discusses the foundations for analysing microarray data sets, genomic data-mining, the creation of standardised nomenclature and data models, clinical applications of functional genomics research, and the future of functional genomics.