Bone Marrow Failure

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Bone marrow failure occurs in individuals who produce an insufficient amount of red blood cells, white blood cells or platelets.

Red blood cells determine how much oxygen needs to be distributed throughout the body's tissue.

White blood cells are constantly helping fight off germs and infections that enter the body.

Bone marrow contains platelets, which clot then helps stop the blood flow when a wound occurs.The cause of bone marrow failure is associated with three types of diseases, fanconi anemia, dyskeratosis congenita, and aplastic anemia.

Fanconi anemia is an inherited blood disorder due to abnormal breakouts in DNA genes.

It is linked to hyperpigmentation, which is the darkening of an area of skin or nails caused by increased melanin.

According to Histopathology, "However, in about 30% of FA patients no physical abnormalities are found".