Analysis of immune memory in B lymphocytes

B cells are a crucial part of the vertebrate adaptive immune system and almost all the vaccines beingused today rely on invoking B cell responses to confer protection against diseases.

Therefore, it is ofutmost importance to understand the biology of these cells.

After being activated by antigenic andco-stimulatory signals, such as from T cells, nave B cells either become memory B cells or plasmacells.

The exact decision-making process that directs these divergent cell fates still needs to beelucidated.