Freeze-drying of Pharmaceuticals and Biopharmaceuticals : Principles and Practice

This book describes the technology of freeze-drying with particular emphasis on the properties of the material to be processed, pre-freezing (formulation) and post-drying (stability and shelf life).

Materials science principles of glasses, as applied to the study of dried, mainly protein-based biopharmaceuticals and analytical methods are also covered.

This book is the first single-author publication, centred mainly on the properties of the materials to be processed, stored and marketed.

It aims to take away the mystique which is still surrounding the technology and points the way to "Stability by Design". "Real Life" cases from the author's archives will be presented and analysed as will dos and don'ts in process and product development.