From enzyme models to model enzymes

This introduction to the exciting area of artificial enzymes starts with a systematic review of the key properties of natural enzymes. This is followed by a summary of the mechanisms involved in the major classes of reactions and a logical progression to the first, rudimentary artificial enzymes catalyzing them. An analysis of the classical design-based approach to catalysis by enzyme mimics leads on to a summary of recent advances in creating and improving catalysts. Key data interpretation skills are introduced in a guided approach that links kinetic measurements with their chemical and biological interpretation.