Toll and toll-like receptors: an immunologic perspective

Until recently innate immunity was viewed as the poorer relative of the sophisticated adaptive immune response.

We now know, however, that these 'higher' immune responses are actually underpinned by an elegantly hewn system of innate immune surveillance.

Discovered first by developmental biologists, again by immunologists, and even by sociologists, Toll receptors have revolutionized our understanding of innate immunology.

Although a small part of a complex system, Toll receptor biology compels us to revisit existing models of self - non-self recognition.Toll and Toll Like Recptors is an eclectic collection of essays, spanning academia and industry.

This volume illustrates how Toll and the Toll-like receptors work and the consequences for us all when they fail.

It looks at Toll structures, what they recognize, and what they 'might' recognize.

This exiting book will be of interest to academics and practitioners in industry, as well as to post graduate students in immunology.